That's something Usona clearly understands in the vision for its new campus.ĭevelopment of psychedelic businesses is scattered, with the biggest clusters in cities like New York, London and Berlin, Schlidt says. ![]() That means there’s a lot of opportunity, not just for drug development, but for all the corresponding therapy and facilitating that goes along with guiding a patient through the experience. Of course, these aren’t drugs you just pick up at the pharmacy and take home. Usona has received interest from more than 15,000 people for its studies, says Tura Patterson, senior director of strategic partnerships. The demand for these new treatments is apparent. Both have gotten breakthrough therapy designations from the FDA, which means their therapies have shown preliminary results that demonstrate they may be significantly better for a serious condition than drugs on the market. Usona Institute is right behind, with a psilocybin therapeutic that could follow a year or two later. ![]() The drug could be approved to be used therapeutically as soon as mid-2023. It is being developed by the non-profit Multidisciplinary Association for Psychedelic Studies (MAPS), which had extraordinary success in a Phase III clinical trial where more than two-thirds of participants with severe PTSD saw their symptoms diminish after three MDMA-assisted therapy sessions. MDMA (Ecstasy/Molly) is on track to be the first psychedelic drug approved by the FDA. The Institute has fulfilled or is considering more than 100 requests for investigational psilocybin by researchers from 14 countries. Usona also allows eligible researchers to apply to use its investigational drug supply in their approved clinical studies. Then they published their process in a peer-reviewed scientific journal as an open access article, which meant people with the right expertise and resources could produce their own supplies for research - a move consistent with Usona’s “open science” practice. Knowing that research was constrained by limited supplies of a pharmaceutical-grade compound, Usona’s medicinal chemists found a more efficient process for synthesizing psilocybin. Usona has been a major force in helping to accelerate psylocibin research. Nearly 30 years after featuring Prozac on its cover, Newsweek in 2021 highlighted magic mushrooms on its cover, saying they may be the next biggest advance in treating depression. Dan Crenshaw, R-Texas, and Alexandria Ocasio-Cortez, D-NY - that would increase access to psychedelic treatments for veterans and active-duty service members with mental health conditions to the must-pass annual National Defense Authorization Act. House of Representatives this month added a pair of amendments - from Reps. ![]() city to decriminalize psilocybin in 2019 since then 13 cities and counties, including several in Michigan, along with the entire state of Oregon have either decriminalized it or made it the lowest law enforcement priority. Each of its four parts focuses on one psychedelic: LSD, psilocybin (mushrooms), MDMA (street names are Ecstasy, Molly) and mescaline (in certain cacti).ĭenver became the first U.S. ![]() Netflix this month introduced a new documentary, “How to Change Your Mind,” based on a book of the same name by Michael Pollan. More: Aaron Rodgers says taking ayahuasca helped improve mental health and spurred MVP seasons Now we’re getting past the hippie thing - fast. The excesses of the hippie hallucinogenic culture essentially caused the shutdown of research into psychedelics.
0 Comments
![]() This page has direct download link for MuMu App Player (Windows and Mac). But first you need to download it and install on your computer. You can play almost all modern apps and games using this player. MuMu is the best Android emulator for playing Android games and apps on Windows PC/laptop and Mac. Therefore, you can trust it as safe and secure emulator. MuMu emulator has its global version and worldwide popular. ![]() Is MuMu safe to download and install on my Windows PC or Mac?Ĭhinese and Russian product are usually notorious for danger and most of people label them hacked without any proof or reason. About MuMu App Player > Check for updatesĪlternatively, you may visit MuMu App Player official website in order to download the latest version for Windows and Mac OS. You can check for update inside emulator by clicking/tap menu > About Us and then tap on check for updates link, which resides next to current version details. How to update MuMu player to latest version? Yes, it is available for Mac but only in Chinese language version, but you can change language to English manually. Is MuMu App Player for Mac officially available? Honestly, it is NOT better but lighter than most of emulators, just like SmartGaGa app player. H ow MuMu player is better than BlueStacks and MEmu player? Its speed and lightweight engine make it one of the fastest Android emulator for playing games on computer. It is an Android emulator with Android 6 (Marshmallow) support. Gamepad controls can be import and export.The portable version does not require any Installation, all you have to do is just to extract the zip file to the directory of your choice and execute the “nemuinstaller.exe” file.Ī shortcut on your desktop will be created by the The classic MuMu Installer requires an internetĬonnection to download the Installation file. Logitheque basically offer two different types ofįiles for Mumu player Installation. Is available as Freeware for all devices. MuMu Player is a free software offered by Netease. Memu app Player is based on the Android 6.0 version and compatible with a large number of applications as well games like PUBG Mobile, FreeFire, Call of Duty Mobile, etc. You just have to extract the Zip file to theĭirectory of your choice and run the file. They also offer a portable version thatĭoesn’t require any installation. Mumu Player basically requires an internet connection Foxburg Country Club is the oldest continuously running golf course in the U.S. The town hosts a Food, Wine and Art Festival each October. There is a hotel, a thriving performing arts center, and restaurants with views of the Allegheny River, a winery, art gallery, and a chocolatier. The town is in the midst of a renaissance. Nestled along the banks of the Allegheny River, you’ll find the charming resort town of Foxburg. The view of the Clarion River Valley is spectacular from Seneca Point and the nearby fire tower. ![]() It is the second most visited park in the state and was named as one of the Top 50 State Parks in the country. ![]() The event will be held at The Advice Store, 5 Market Pavement, Basildon, SS14 1DD, on Friday 26 August from 11am to 2pm.Crafters Day at Clarion’s Autumn Leaf FestivalĮach August the Clarion County Airport, near Shippenville, hosts an Open House where you can get up close to vintage planes and classic cars and enjoy a fly over by historically significant aircraft.Ĭook Forest State Park is a national treasure with 350 year-old trees and all kinds of fun outdoor family activities. The Advice Store is a fantastic asset for our community and one that will benefit many of our young people in taking the next step in their career." "With a range of exhibitors on hand to talk through apprenticeships, education programmes, career advice, employability support, and much more, there is something to suit personal circumstances. Young people who haven't received their results but would benefit from attending are also welcome.Įxhibitors at the event include ACL, Clarion Futures, Debut Academy, HeadsUp, LifeSkills, SECTA, USP and Prince's Trust.Ĭllr Anthony Hedley, Basildon Council's Cabinet Member for Economic Growth and Business Engagement said "We know receiving exam results can be an emotional and unsettling time, the 'What next' event is a great opportunity for young people to explore their options, whatever their results may be. ![]() 'What next?' is specially designed to support those who may feel anxious about opportunities available to them. These include apprenticeships, supported internships, training to enter job sectors such as beauty and construction, or study programmes to improve grades. This special event will be held at Basildon Council's Advice Store in Basildon town centre.Ī week on from A-level results and the day after GCSE results, young people will speak to a wide range of organisations offering a variety of opportunities for their next steps. ![]() This is a limitation with pretty much any data recovery software.īecause generic names can make sorting through content difficult, Data Rescue lets you preview returned data. Folder content displays in the central pane.įiles deleted from Windows cannot be recovered with their filenames. ![]() Once your scan completes, you can navigate found content with a file tree pane on the left side of the wizard. While scanning, a progress bar will keep you informed of how much of the scan has completed and how much time remains. Quick scan can also be used to recover files from a non-mounting partition that still has its file system (i.e., it isn’t RAW or formatted).įor long deleted content, you’ll likely need to execute a deep scan. When you run a quick scan, Data Rescue can usually recover files that have been recently deleted. Afterwards, you’ll be asked whether you want to run a quick or deep scan. On the next screen, you can choose to load scan results from a prior scan or start a new scan. Once you’ve selected the partition you want to work with, hit the “scan” button. We tested both processes during our review. If you’re trying to recover a deleted, corrupted or formatted partition, though, you’ll want to do a full drive scan. If you’re looking to recover a lost or deleted file, just pick the partition the file was on. You can pick a particular partition or scan the entire hard drive. The program should detect any partitions on your hard drive. Once the wizard starts, your first step will be to pick a volume to scan. For example, with Stellar Data Recovery Pro (read our Stellar Data Recovery review), you can select which types of files you want to scan for, which reduces scan time. Overall, we didn’t find the wizard packed as many options as a few other data recovery tools, though. The recovery process provides a fairly intuitive experience thanks to a straightforward wizard. In this segment, we’ll walk you through the Data Rescue PC4 user experience to help you get a feel for what the software can do.
Money gathered then goes into building the stuff you just researched. Special items, on the other hand, can increase the parameters of buildings, shops, and commerce.Īll these systems feed into the overall research and build structure buildings dish out research points at unpredictable intervals, and this gives you the power to research new buildings. People, in order to fair well in the workplace, need to earn bonus statistics given nebulously from these buildings. A grid-based placing system keeps everything as neat and tidy as can be, and a UI choked with options and graphs and additional mechanics will be where you spend the most of your time.īuildings, in order to be efficient enough to profit, need to be paired with other very specific buildings. You’ll build houses and then people will buy them you’ll build buildings and then people will work in them you’ll buy cafes, and arcades, and pastures, and parks, and then people will spend money in them. Venture Towns, for the most part, is a carbon copy of Oh! Edo Towns set in the modern day. My recommendation is rather weak: I’d say buy it… but only if you dug Oh! Edo Towns a lot. The prices in keyshops are often cheaper than in official shops, but there are certain risks involved and purchasing through unauthorized resellers won’t support the game developers directly.My feelings on Kairosoft’s new simulation, Venture Towns, are mixed, leaning on negative. Keyshops resell the game keys from undisclosed sources. Official stores retail the game keys by getting them directly through the game developer or publisher. Choose between official stores and keyshops. ![]() For example, if you want to get Venture Towns Steam key and activate it on Steam, pick the shop that has a Steam icon. You will find this information on the game card in the form of a launcher icon. When checking the offers for Venture Towns, make sure that the key is activated through the DRM of your choice.Price is not the only criteria you should bear in mind when buying pc games through GG.deals. Which Venture Towns shop to choose? What’s the difference between official stores and keyshops? Look out for these giveaways and actively participate for better chances of winning the prize!Įven if Venture Towns free download is not available, you can always save up and get the key at the lowest possible price using GG.deals comparison engine. GG.deals sometimes organizes giveaways where you can win good games for completing short tasks.If there is a way to get Venture Towns for free, you will be the first to know! There are also regular giveaways on Epic Games Store. Stores like Humble Bundle or Indie Gala frequently give away free Steam keys for promotional purposes. ![]()
Settled they may be, but the Vikings haven’t forgotten how to wring coin out of civilians. One does not cage the wolf without consequence… He and his men were allowed to return to East Anglia and settle – provided they kept Alfred’s peace, of course.ĭefeated, but never humbled, the Vikings seethe with an all-consuming rage. Three weeks later, under the terms of his capitulation, Guthrum was baptised into Christianity and became Alfred’s adoptive son. After a fortnight of starvation, the invaders surrendered. Flush with success, Alfred’s men gave chase and laid siege. Bested in the field, his forces retreated in disarray to a nearby fortress. The army was reinforced – and later divided – but ultimately endured until the Battle of Edington in 878 AD, where its leader Guthrum met his match in the young King Alfred and his West Saxon army. Over the next 15 years the Vikings ranged high and low, from Wessex to The Clyde, conquering towns, claiming victories and suffering their share of defeats. The army wintered there before setting off north towards York, where they were again paid off while establishing control of Northumbria. The locals made peaceful overtures, offering the invaders their horses and hospitality to allay conflict. ![]() Ragnar’s sons led the Great Viking Army and made landfall in East Anglia that same year. A sense of organisation crept into their plans, and in due course the Danes, supported by the Swedes and Norwegians, raised a great army with the intention of conquering Britannia and avenging the death of the legendary Viking warlord Ragnar Lothbrok, executed by the King of Northumbria in 865 AD. What began as sporadic coastal raids intensified over time as the Vikings began to glean the scale of plunder Britannia could offer. ![]() ![]() The previous century had seen escalating Viking incursions across the isles. A bitter pill for the invaders to swallow, in light of their grand vision for a new Scandinavian kingdom. In 878 AD, the Great Viking Army was defeated by King Alfred and faced a new life of enforced settlement in the east of Britannia. This filter only works is there is no alpha channel Mapping colour percentages of an imageĮg, to work out percentage of foamboard sheet used for a model.Ĭonvert image.jpg -format %c histogram:info:- | sort -nrĬonvert image.jpg -colorspace RGB -format %c histogram:info:- | sort -nr Sudo systemctl set-default multi-user.target To mount external usb hard disk at boot when booting to commandlinr mode only, Mint 20.1 edit /etc/netplan/1-network-manager-all.yaml as follows-įor the video stream select a different format (ie, not "Copy"). Mint 20.x uses netplan, so the old method of editing /etc/network/interfacesġ. ( first remove blank lines from the file using # Apple devices won't play the audio if it is not in aac format.įfmpeg -i spot-video-only.mp4 -i spot-lownoise-normalised.mp3 -shortest -c:v copy -c:a libvo_aacenc -b:a 256k Spot\'s_sad_and_happy_day_aac.mp4įormat a text file with 4 fields on separate line into a 4 column tableĮ.g. # and merge video and audio streams, transcoding the audio to "aac" format. Mv spot-lownoise.mp3 spot-lownoise-normalised.mp3įfmpeg -i Spot\'s_sad_and_happy_day.mp4 -codec copy -an spot-video-only.mp4 # used normalize-mp3 to make the sound loud enough # used Audacity to reduce the noise, which was constant background "white noise" # made a copy, in case I need to check the original audio later.Ĭp Spot\'s_sad_and_happy_day.mp3 spot.mp3 Here's what I did to make it acceptable.įfmpeg -i Spot\'s_sad_and_happy_day.mp4 Spot\'s_sad_and_happy_day.mp3 Sound had noise and the voice was too quiet. I found this superior to posterazor which required trimming of the pages and lacked alignmenbt cues.Ī friend sent me a video made on an iPad. ![]() When printed the 8 pages can be taped edge to edge (no overlap or trimming needed) to make the full-size plan/poster. p 30x20inch means a 30x20 inch size plan/posterįish-fuse-30x20inch.pdf is the 8-A4 page output file. m A4 means use A4 size paper in the printer Pdfposter -m A4 -p 30x20inch the_fish_v2.pdf fish-fuse-30x20inch.pdf I wanted to print a free model plane plan, sized at 20x30 inches. Printing a large plan or poster when you only have a home printer (eg, A4 paper) ![]() Merging 2 videos even with different codec and format settingsįfmpeg -i who-is-best-1.mp4 -i out.mp4 -filter_complex " concat=n=2:v=1:a=1 " -map "" -map "" merged-video.mp4 Weex gets segmentation fault, core dumped, on Mint 20.1Ĭreating a video with a single slide and some audioįfmpeg -loop 1 -i who-is-best-1280x720.png -i who-is-2-audio-a.mp3 -c:v h264 -tune stillimage -c:a aac -b:a 192k -pix_fmt yuv420p -shortest out.mp4 I removed 2 snap apps I had plus the snapd support stuff and it is now fine again. VIDEOSPEEDUP=`echo "scale=4 1 / $SPEEDUP" | bc`įfmpeg -i $VID -filter_complex "setpts=0.85*PTS atempo=1.1765" -map "" -map "" $NEWVIDįor colour in black white yellow red brown do cp 2faces.jpg 2faces-$colour.jpg doneĪpple iMac 24 inch 2008, 6GB ram, 1TB disk ![]() ![]() # also shrinks the video, which is always good!Įcho Usage: speedup-video.sh videofile speedupĮcho where speedup is, eg, 110 for 10% faster The echo commands cause "junk" characters to interfere with the arguments given to scp or rsync. Solution was to remove all echo commands from both the. That's it, you will be able to view the minimized windows :) Right click on panel - select add to panel - scroll down and chose windows list all file minimize - will show on panel. How do I get my minimized window back in Linux? Lost minimised windows in Linux Mint Mate Replaces frames from the beginning to 138 seconds with the image. Hope they help you tooįfmpeg -i 10_July_2022,_An_Ancient_Atheism,_James_Stone.mp4 -i an_ancient_atheism.jpg -filter_complex "scale2ref overlay=enable='between(t,0,138)'" -c:a copy out.mp4 ![]() It is free and extremely light on memory and system. ![]() And, the interface has that old school charm to it which makes it easy to use. Gamma Panel is a brightness controller app for Windows 10 which lets you customize contrast, screen brightness and gamma settings, all with a single click. You can disable the software if you wish to leave the screen tone as it is.For instance, during sunset it’ll make your computer look like indoor light In fact it adjusts the screen brightness as per the room lighting.To control display brightness f.lux adjusts the color of your monitor according to the time of the day.Here’s a Windows 10 software that will help you manage display brightness so that you are not again hit in the face with bad lighting. The monitor dimmer software also has a force rest feature that prevents you from skipping breaksĮver woke up with a bright sunshine and immediately got blinded by your monitor screen just because it had poor lighting.It even warns you to take breaks at intervals and prompts you to make changes to the color temperatures.Accordingly you can increase or decrease the brightness and the warmth by moving the slider to the right or left respectively.There are several different modes you can choose from – custom, game, movie, reading, night, office, normal and editing.By default it decreases the brightness by 10% After installation CareUEyes automatically increases or decreases the brightness of your monitor.It basically adjusts the gamma values of the screen to make it darker or brighter. CareUEyes is an intelligent screen dimmer software that takes into account all types of screens and monitors – TFT, LED and LCD and works efficiently with both dark and light environments. ![]() That means the x coordinate will be 1.786 after rounding to three decimal places. We still do not know the exact location of the minimum point, but we know that its x coordinate is between 1.786Īnd 1.7864. There are two different x values that correspond to the lowest You need to move left to get to the minimum point. To get it back, click the Trace button again. The viewing rectangle removes the trace point. = -8.19, and set the viewing rectangle to these coordinates by clicking the Reset button. In this example we will set the view coordinates. Or set the coordinates of the viewing rectangle. There are several ways to do this with the Grapher: Zoom In, Zoom Box, So we need to improve our estimate by zooming in on the minimum point. If the second decimal place wereĪ 7, then the value would round to 1.8. Note that we do not yet have enough information to report the x value with even one decimal place accuracy,īecause if the second decimal place were a 4, then the value would round to 1.7. The points in the table show that the real minimum point has an x coordinate somewhere between 1.7333333 andġ.8666667. May may be slightly different from those above. Note that different Java implementations will compute and report different accuracies, so the values you find The table below lists the coordinates of these ![]() Is set to 1, and then find the points on either side of this point. Find this trace point, make sure that the Step Size Point to get an idea of how close we are. We need to look at the trace points on either side of this This is not the exact location of the minimum point. Using the default view, the lowest point found while tracing near the minimum point is (1.8, -8.208). It is possible to move faster with the enter key than with the mouse. Also notice that once you have clicked the > button, then you can use the enter key to move further right. Select a larger Step Size from the pull down menu, then the trace point moves farther with eachĬlick. If x, the trace point moves to the right, staying on the graph of f. Similarly, (2Lx) is 1 for 2 2, the formula evaluates to x - 1. The factor (xLE2) has the value 1 for x 2. To express f in a single formula for the Java Grapher or Java Calculator we write Simply enter theįormula x^2 - 3 in the f text box and click graph. (b) Verify that your sketch is correct by using the Java Grapher to graph f. (a) Plot the five points on the graph of f from the table above, and based on these points, sketch the graph Theįollowing table shows several values for x and the function f evaluated at those numbers.Įach column of numbers in the table holds the coordinates of a point on the graph of f. Choose a value for the first coordinate, then evaluate f at that number to find the second coordinate. The graph of f(x) in this example is the graph of y = x 2 - 3. Graphs of functions are graphs of equations that have been solved for y! We simply choose a number for x, then compute the corresponding value Is easy to find points that are on the graph. Recall that when we introduced graphs of equations we noted that if we can solve the equation for y, then it So, the graph of a function if a special case of the graph The graph of f to be the graph of the equation y = f(x). The graph of a function f is the set of all points in the plane of the form (x, f(x)). ![]() The other cash flows will need to be discounted by the number of years associated with each cash flow. This just means that we really aren’t discounting the first cash flow because you would be paying for the project at the present time, so the present value of the first cash flow is just that, the first cash flow at face value. We discount our first cash flow, a cash outflow to be precise, by zero years. Now that we have a good visual of what the project looks like financially, let’s begin our NPV calculation. The following years you will receive more cash due to an increase in production of widgets. Remember, at time 0 (the present day), you must outlay $500,000 in order to receive the new piece of machinery. We have our rate at 6% listed first, and you can see below each year and the cash flow associated with that year. You might consider setting up a table for this project that looks something like that of the one below: It is usually easiest both to see and set up the calculation by looking at a table of cash flows. What is the net present value of your potential investment? The rate of return of an alternative project is 6%. Your analysts are projecting that the new machine will produce cash flows of $210,000 in Year 1, $237,000 in Year 2, and $265,000 in Year 3. Thus, you expect cash flows to increase over time as your employees become more familiar with the equipment. This machine operates differently than the one your company currently uses to produce widgets, so it may take time for your employees to get used to operating the new equipment. This new piece of machinery costs $500,000 for a three-year lease, but your hope is that your company will operate more efficiently and generate higher cash flows as a result of this new machine. ![]() Suppose you as the investor are looking at investing in a project for your company that would extend to you the ownership of a new piece of machinery that may help your business produce widgets more efficiently. ![]() This methodology follows from compound interest. To discount a cash flow, simply divide the cash flow by one plus the discount rate, raised to the number of periods you are discounting. This means that our cash flow for the first time period of the project would be discounted once, the cash flow in the second time period would be discounted twice, and so forth. The way we do this is through the discount rate, r, and each cash flow is discounted by the number of time periods that cash flow is away from the present date. Now, this is not always the case, since cash flows typically are variable however, we must still account for time. This means that the present value of the cash flows decreases. Just by thinking of things intuitively by the time value of money, if you have a time series of identical cash flows, the cash flow in the first time period will be the most valuable, the cash flow in the second time period will be the second most valuable, and so forth. The alternative project is investing the dollar, and the rate of return for that alternative project is the rate that your dollar would grow over one year. If you don’t invest that dollar, you will still have that same dollar bill in your pocket next year however, if you invest it, you could have more than that dollar one year from now. The way we calculate the present value is through our discount rate, r, which is the rate of return we could expect from alternative projects. This way of thinking about NPV breaks it down into two parts, but the formula takes care of both of these parts simultaneously. ![]() cash you earn from the project, less the present value of all cash outflows, i.e. You can think of NPV in different ways, but I think the easiest way is to think of it is as the sum of the present value all cash inflows, i.e. |